At a glance
BioShock Infinite has a Mac version: Steam sells it for macOS. The Mac requirements list only Intel: on Apple Silicon Rosetta 2 runs it, and old Mac versions sometimes do not start on current macOS. Try it in Steam for Mac first.
BioShock Infinite came out on Steam on 25 March 2013, made by Irrational Games.
What your Mac needs
The Mac requirements list only Intel.
Minimum macOS in the Steam requirements: 10.12.
Steam requirements list at least 4 GB of memory for BioShock Infinite.
Allow about 30 GB of disk space for the Mac version.
How to play
Open Steam for Mac and install BioShock Infinite as usual.
If the Mac version will not start, you can install the Windows version through Uncork: download Uncork, sign in to Steam and install BioShock Infinite from there (20 GB). We have not tested it ourselves.
The Windows version through Uncork needs a Mac with Apple Silicon (M1 or newer).
BioShock Infinite uses DirectX 10: Uncork renders it with D3DMetal.