At a glance
BioShock 2 Remastered has a Mac version: Steam sells it for macOS. The Mac requirements list only Intel: on Apple Silicon Rosetta 2 runs it, and old Mac versions sometimes do not start on current macOS. Try it in Steam for Mac first.
BioShock 2 Remastered came out on Steam on 15 September 2016, made by 2K Marin, 2K China, Digital Extremes, 2K Australia, Blind Squirrel.
Mac version by Feral Interactive.
What your Mac needs
The Mac requirements list only Intel.
Minimum macOS in the Steam requirements: 10.15.4.
Steam requirements list at least 8 GB of memory for BioShock 2 Remastered.
Allow about 22 GB of disk space for the Mac version.
How to play
Open Steam for Mac and install BioShock 2 Remastered as usual.
If the Mac version will not start, you can install the Windows version through Uncork: download Uncork, sign in to Steam and install BioShock 2 Remastered from there (25 GB). We have not tested it ourselves.
The Windows version through Uncork needs a Mac with Apple Silicon (M1 or newer).
BioShock 2 Remastered uses DirectX 11: Uncork renders it with D3DMetal.