At a glance
Serious Sam 3: BFE has a Mac version: Steam sells it for macOS. The Mac requirements list only Intel: on Apple Silicon Rosetta 2 runs it, and old Mac versions sometimes do not start on current macOS. Try it in Steam for Mac first.
Serious Sam 3: BFE came out on Steam on 22 November 2011, made by Croteam.
What your Mac needs
The Mac requirements list only Intel.
Minimum macOS in the Steam requirements: 10.5.8.
Steam requirements list at least 2 GB of memory for Serious Sam 3: BFE; 4 GB recommended.
Allow about 6 GB of disk space for the Mac version.
How to play
Open Steam for Mac and install Serious Sam 3: BFE as usual.
If the Mac version will not start, you can install the Windows version through Uncork: download Uncork, sign in to Steam and install Serious Sam 3: BFE from there (4 GB). We have not tested it ourselves.
The Windows version through Uncork needs a Mac with Apple Silicon (M1 or newer).
Serious Sam 3: BFE uses DirectX 9.0c: Uncork renders it with its built-in graphics.