At a glance
Oxygen Not Included has a Mac version: Steam sells it for macOS. The Mac requirements list only Intel: on Apple Silicon Rosetta 2 runs it, and old Mac versions sometimes do not start on current macOS. Try it in Steam for Mac first.
Oxygen Not Included came out on Steam on 30 July 2019, made by Klei Entertainment.
What your Mac needs
The Mac requirements list only Intel.
Minimum macOS in the Steam requirements: 12.
Steam requirements list at least 8 GB of memory for Oxygen Not Included; 16 GB recommended.
Allow about 3 GB of disk space for the Mac version.
How to play
Open Steam for Mac and install Oxygen Not Included as usual.
If the Mac version will not start, you can install the Windows version through Uncork: download Uncork, sign in to Steam and install Oxygen Not Included from there (3 GB). We have not tested it ourselves.
The Windows version through Uncork needs a Mac with Apple Silicon (M1 or newer).
Oxygen Not Included uses DirectX 11: Uncork renders it with D3DMetal.